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IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM)
Cancer immunotherapy has been shown to enhance established treatment regimens. We evaluated the potential reinforcing effect of IL-15 in trastuzumab treated humanized tumor mice (HTM) which were generated by concurrent transplantation of neonatal NOD-scid IL2Rγnull mice with human hematopoietic stem...
Autores principales: | Wege, Anja K, Weber, Florian, Kroemer, Alexander, Ortmann, Olaf, Nimmerjahn, Falk, Brockhoff, Gero |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356837/ https://www.ncbi.nlm.nih.gov/pubmed/27835865 http://dx.doi.org/10.18632/oncotarget.13159 |
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