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Use of capture-based next-generation sequencing to detect ALK fusion in plasma cell-free DNA of patients with non-small-cell lung cancer

Capture-based next-generation sequencing (NGS) is a potentially useful diagnostic method to measure tumor tissue DNA in blood as it can identify concordant mutations between cell-free DNA (cfDNA) and primary tumor DNA in lung cancer patients. In this study, the sensitivity, specificity and accuracy...

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Detalles Bibliográficos
Autores principales: Cui, Shaohua, Zhang, Wei, Xiong, Liwen, Pan, Feng, Niu, Yanjie, Chu, Tianqing, Wang, Huimin, Zhao, Yizhuo, Jiang, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356840/
https://www.ncbi.nlm.nih.gov/pubmed/27926526
http://dx.doi.org/10.18632/oncotarget.13741