Genetic and epigenetic characterization of the BRCA1 gene in Brazilian women at-risk for hereditary breast cancer

This study aimed to characterize women at-risk for hereditary BC regarding their clinical and molecular characteristics (mutation and methylation in the BRCA1 gene) and correlate the gene expression levels with histopathological, clinical and family history information. BRCA1 real time qPCR was perf...

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Detalles Bibliográficos
Autores principales: Felicio, Paula Silva, Melendez, Matias Eliseo, Arantes, Lidia Maria Rebolho Batista, Kerr, Ligia Maria, Carraro, Dirce Maria, Grasel, Rebeca Silveira, Campacci, Natalia, Scapulatempo-Neto, Cristovam, Fernandes, Gabriela Carvalho, de Carolina, Ana Carvalho, Palmero, Edenir Inêz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356847/
https://www.ncbi.nlm.nih.gov/pubmed/27926510
http://dx.doi.org/10.18632/oncotarget.13750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356847/
https://www.ncbi.nlm.nih.gov/pubmed/27926510
http://dx.doi.org/10.18632/oncotarget.13750

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