Cargando…

Changes in the methylation status of the Oct3/4, Nanog, and Sox2 promoters in stem cells during regeneration of rat tracheal epithelium after injury

We investigated the relationship between promoter methylation and tracheal stem cell activation. We developed a model of rat tracheal epithelium regeneration after 5-fluorouracil (5-FU)-induced injury. Using immunohistochemistry and Western blotting, the expression levels of the stem cell pluripoten...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Ying, Song, Nan, Li, Xin, Han, Ying, Ren, Zihan, Xu, Jing-xian, Han, Yu-chen, Li, Fang, Jia, Xinshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356857/
https://www.ncbi.nlm.nih.gov/pubmed/27935870
http://dx.doi.org/10.18632/oncotarget.13818