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CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways

CD147 null mutant male mice are infertile with arrested spermatogenesis and increased apoptotic germ cells. Our previous studies have shown that CD147 prevents apoptosis in mouse spermatocytes but not spermatogonia. However, the underlying mechanism remains elusive. In the present study, we aim to d...

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Detalles Bibliográficos
Autores principales: Wang, Chaoqun, Fok, Kin Lam, Cai, Zhiming, Chen, Hao, Chan, Hsiao Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356870/
https://www.ncbi.nlm.nih.gov/pubmed/27902973
http://dx.doi.org/10.18632/oncotarget.13624