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SAHA and/or MG132 reverse the aggressive phenotypes of glioma cells: An in vitro and vivo study

To elucidate the anti-tumor effects and molecular mechanisms of SAHA (a histone deacetylase inhibitor) and MG132 (a proteasome inhibitor) on the aggressive phenotypes of glioma cells, we treated U87 and U251 cells with SAHA or/and MG132, and detected phenotypes’ assays with phenotype-related molecul...

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Detalles Bibliográficos
Autores principales: Yang, Xue-feng, Zhao, Zhi-juan, Liu, Jia-jie, Yang, Xiang-hong, Gao, Yang, Zhao, Shuang, Shi, Shuai, Huang, Ke-qiang, Zheng, Hua-chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356872/
https://www.ncbi.nlm.nih.gov/pubmed/27911270
http://dx.doi.org/10.18632/oncotarget.13680