Blocking EZH2 methylation transferase activity by GSK126 decreases stem cell-like myeloma cells

EZH2 is a critical epigenetic regulator that is deregulated in various types of cancers including multiple myeloma (MM). In the present study, we hypothesized that targeting EZH2 might induce apoptosis in myeloma cells including stem cell-like cells (CSCs). We investigated the effect of EZH2 inhibit...

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Detalles Bibliográficos
Autores principales: Zeng, Delong, Liu, Maoxing, Pan, Jingxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356890/
https://www.ncbi.nlm.nih.gov/pubmed/27926488
http://dx.doi.org/10.18632/oncotarget.13773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356890/
https://www.ncbi.nlm.nih.gov/pubmed/27926488
http://dx.doi.org/10.18632/oncotarget.13773

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