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Blocking EZH2 methylation transferase activity by GSK126 decreases stem cell-like myeloma cells
EZH2 is a critical epigenetic regulator that is deregulated in various types of cancers including multiple myeloma (MM). In the present study, we hypothesized that targeting EZH2 might induce apoptosis in myeloma cells including stem cell-like cells (CSCs). We investigated the effect of EZH2 inhibit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356890/ https://www.ncbi.nlm.nih.gov/pubmed/27926488 http://dx.doi.org/10.18632/oncotarget.13773 |