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FGFR4 polymorphic alleles modulate mitochondrial respiration: A novel target for somatostatin analog action in pituitary tumors

We reported that a single nucleotide polymorphism (SNP) at codon 388 of the fibroblast growth factor receptor 4 (FGFR4-Gly388Arg) can result in distinct proteins that alter pituitary cell growth and function. Here, we examined the differential properties of the available therapeutic somatostatin ana...

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Detalles Bibliográficos
Autores principales: Ezzat, Shereen, Wang, Ri, Pintilie, Melania, Asa, Sylvia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356897/
https://www.ncbi.nlm.nih.gov/pubmed/27966451
http://dx.doi.org/10.18632/oncotarget.13843