Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption

Tumor cells rely on high concentrations of amino acids to support their growth and proliferation. Although increased macropinocytic uptake and lysosomal degradation of the most abundant serum protein, albumin, in Ras-transformed cells can meet these demands, it is not understood how the majority of...

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Detalles Bibliográficos
Autores principales: Swiercz, Rafal, Mo, Min, Khare, Priyanka, Schneider, Zita, Ober, Raimund J, Ward, Elizabeth Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356901/
https://www.ncbi.nlm.nih.gov/pubmed/27974681
http://dx.doi.org/10.18632/oncotarget.13869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356901/
https://www.ncbi.nlm.nih.gov/pubmed/27974681
http://dx.doi.org/10.18632/oncotarget.13869

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