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Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption
Tumor cells rely on high concentrations of amino acids to support their growth and proliferation. Although increased macropinocytic uptake and lysosomal degradation of the most abundant serum protein, albumin, in Ras-transformed cells can meet these demands, it is not understood how the majority of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356901/ https://www.ncbi.nlm.nih.gov/pubmed/27974681 http://dx.doi.org/10.18632/oncotarget.13869 |