Cargando…

How are base excision DNA repair pathways deployed in vivo?

Since the discovery of the base excision repair (BER) system for DNA more than 40 years ago, new branches of the pathway have been revealed at the biochemical level by in vitro studies. Largely for technical reasons, however, the confirmation of these subpathways in vivo has been elusive. We review...

Descripción completa

Detalles Bibliográficos
Autores principales: Thapar, Upasna, Demple, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357041/
https://www.ncbi.nlm.nih.gov/pubmed/28357058
http://dx.doi.org/10.12688/f1000research.10538.1