Direct and enhanced delivery of nanoliposomes of anti schizophrenic agent to the brain through nasal route

The problem of inadequate oral bioavailability of Quetiapine Fumarate, a lipophilic drug used for schizophrenia, due to hepatic metabolism and repulsion by brain barrier was attempted in this study. Combination of two approaches, viz. Quetiapine inclusion into the liposomal carrier for better diffus...

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Detalles Bibliográficos
Autores principales: Upadhyay, Pratik, Trivedi, Jatin, Pundarikakshudu, Kilambi, Sheth, Navin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357100/
https://www.ncbi.nlm.nih.gov/pubmed/28344488
http://dx.doi.org/10.1016/j.jsps.2016.07.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357100/
https://www.ncbi.nlm.nih.gov/pubmed/28344488
http://dx.doi.org/10.1016/j.jsps.2016.07.003

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