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Direct and enhanced delivery of nanoliposomes of anti schizophrenic agent to the brain through nasal route
The problem of inadequate oral bioavailability of Quetiapine Fumarate, a lipophilic drug used for schizophrenia, due to hepatic metabolism and repulsion by brain barrier was attempted in this study. Combination of two approaches, viz. Quetiapine inclusion into the liposomal carrier for better diffus...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357100/ https://www.ncbi.nlm.nih.gov/pubmed/28344488 http://dx.doi.org/10.1016/j.jsps.2016.07.003 |