Investigation of the in vitro performance difference of drug-Soluplus® and drug-PEG 6000 dispersions when prepared using spray drying or lyophilization

Purpose: To evaluate the physicochemical and in vitro characteristics of solid dispersions using BCS II model drugs with Soluplus® and one of its component homopolymers, PEG 6000. Methods: Nifedipine (NIF) and sulfamethoxazole (SMX) of 99.3% and 99.5% purity, respectively, were selected as BCS II mo...

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Detalles Bibliográficos
Autores principales: Altamimi, Mohammad A., Neau, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357108/
https://www.ncbi.nlm.nih.gov/pubmed/28344498
http://dx.doi.org/10.1016/j.jsps.2016.09.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357108/
https://www.ncbi.nlm.nih.gov/pubmed/28344498
http://dx.doi.org/10.1016/j.jsps.2016.09.013

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