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A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications

Specific niches within the tumor bone marrow (BM) microenvironment afford a sanctuary for multiple myeloma (MM) clones due to stromal cell-tumor cell interactions, which confer survival advantage and drug resistance. Defining the sequelae of tumor cell interactions within the MM niches on an individ...

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Detalles Bibliográficos
Autores principales: Jakubikova, Jana, Cholujova, Danka, Hideshima, Teru, Gronesova, Paulina, Soltysova, Andrea, Harada, Takeshi, Joo, Jungnam, Kong, Sun-Young, Szalat, Raphael E., Richardson, Paul G., Munshi, Nikhil C., Dorfman, David M., Anderson, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357212/
https://www.ncbi.nlm.nih.gov/pubmed/27764795
http://dx.doi.org/10.18632/oncotarget.12643