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A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications
Specific niches within the tumor bone marrow (BM) microenvironment afford a sanctuary for multiple myeloma (MM) clones due to stromal cell-tumor cell interactions, which confer survival advantage and drug resistance. Defining the sequelae of tumor cell interactions within the MM niches on an individ...
Autores principales: | Jakubikova, Jana, Cholujova, Danka, Hideshima, Teru, Gronesova, Paulina, Soltysova, Andrea, Harada, Takeshi, Joo, Jungnam, Kong, Sun-Young, Szalat, Raphael E., Richardson, Paul G., Munshi, Nikhil C., Dorfman, David M., Anderson, Kenneth C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357212/ https://www.ncbi.nlm.nih.gov/pubmed/27764795 http://dx.doi.org/10.18632/oncotarget.12643 |
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