Heat shock transcription factor 1 protects against pressure overload-induced cardiac fibrosis via Smad3

ABSTRACT: Fibrotic cardiac muscle exhibits high stiffness and low compliance which are major risk factors of heart failure. Although heat shock transcription factor 1 (HSF1) was identified as an intrinsic cardioprotective factor, the role that HSF1 plays in cardiac fibrosis remains unclear. Our stud...

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Detalles Bibliográficos
Autores principales: Zhou, Ning, Ye, Yong, Wang, Xingxu, Ma, Ben, Wu, Jian, Li, Lei, Wang, Lin, Wang, Dao Wen, Zou, Yunzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357304/
https://www.ncbi.nlm.nih.gov/pubmed/28091697
http://dx.doi.org/10.1007/s00109-016-1504-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357304/
https://www.ncbi.nlm.nih.gov/pubmed/28091697
http://dx.doi.org/10.1007/s00109-016-1504-2

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