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Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies

Systemic treatment of cancer requires tumour-selective therapies that eliminate cancer cells yet preserve healthy tissues from undesired damage. Tumoral transformation is associated with profound effects in translational reprogramming of gene expression, such that tumour-specific translational regul...

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Detalles Bibliográficos
Autores principales: Villanueva, Eneko, Navarro, Pilar, Rovira-Rigau, Maria, Sibilio, Annarita, Méndez, Raúl, Fillat, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357308/
https://www.ncbi.nlm.nih.gov/pubmed/28300077
http://dx.doi.org/10.1038/ncomms14833