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Developmental and loco-like effects of a swainsonine-induced inhibition of α-mannosidase in the honey bee, Apis mellifera

BACKGROUND: Deficiencies in lysosomal a-mannosidase (LAM) activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. Yet, epialleles adversely affecting LAM expression exist in the honey bee population suggesting that they...

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Detalles Bibliográficos
Autores principales: Wedd, Laura, Ashby, Regan, Foret, Sylvain, Maleszka, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357340/
https://www.ncbi.nlm.nih.gov/pubmed/28321369
http://dx.doi.org/10.7717/peerj.3109