Effect of method of deduplication on estimation of differential gene expression using RNA-seq

BACKGROUND: RNA-seq is a useful tool for analysis of gene expression. However, its robustness is greatly affected by a number of artifacts. One of them is the presence of duplicated reads. RESULTS: To infer the influence of different methods of removal of duplicated reads on estimation of gene expre...

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Detalles Bibliográficos
Autores principales: Klepikova, Anna V., Kasianov, Artem S., Chesnokov, Mikhail S., Lazarevich, Natalia L., Penin, Aleksey A., Logacheva, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357343/
https://www.ncbi.nlm.nih.gov/pubmed/28321364
http://dx.doi.org/10.7717/peerj.3091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357343/
https://www.ncbi.nlm.nih.gov/pubmed/28321364
http://dx.doi.org/10.7717/peerj.3091

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