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Effect of method of deduplication on estimation of differential gene expression using RNA-seq
BACKGROUND: RNA-seq is a useful tool for analysis of gene expression. However, its robustness is greatly affected by a number of artifacts. One of them is the presence of duplicated reads. RESULTS: To infer the influence of different methods of removal of duplicated reads on estimation of gene expre...
Autores principales: | Klepikova, Anna V., Kasianov, Artem S., Chesnokov, Mikhail S., Lazarevich, Natalia L., Penin, Aleksey A., Logacheva, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357343/ https://www.ncbi.nlm.nih.gov/pubmed/28321364 http://dx.doi.org/10.7717/peerj.3091 |
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