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The Role of Ca(2+) Imbalance in the Induction of Acute Oxidative Stress and Cytotoxicity in Cultured Rat Cerebellar Granule Cells Challenged with Tetrabromobisphenol A

Using primary cultures of rat cerebellar granule cells (CGC) we examined the role of calcium transients induced by tetrabromobisphenol A (TBBPA) in triggering oxidative stress and cytotoxicity. CGC were exposed for 30 min to 10 or 25 µM TBBPA. Changes in intracellular calcium concentration ([Ca(2+)]...

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Detalles Bibliográficos
Autores principales: Zieminska, Elzbieta, Lenart, Jacek, Diamandakis, Dominik, Lazarewicz, Jerzy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357503/
https://www.ncbi.nlm.nih.gov/pubmed/27718046
http://dx.doi.org/10.1007/s11064-016-2075-x