Loss of PI3K p110α in the Adipose Tissue Results in Infertility and Delayed Puberty Onset in Male Mice

Deletion of PI3K catalytic subunit p110α in adipose tissue (aP2-Cre/p110α(flx/flx), α−/− hereafter) results in increased adiposity, glucose intolerance, and liver steatosis. Because this endocrine organ releases hormones like leptin, which are important in reproductive physiology, we investigated th...

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Detalles Bibliográficos
Autores principales: Nelson, Victoria L. Boughton, Negrón, Ariel L., Reid, Inefta, Thomas, Justin A., Yang, Leon, Lin, Richard Z., Acosta-Martínez, Maricedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357525/
https://www.ncbi.nlm.nih.gov/pubmed/28357399
http://dx.doi.org/10.1155/2017/3756089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357525/
https://www.ncbi.nlm.nih.gov/pubmed/28357399
http://dx.doi.org/10.1155/2017/3756089

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