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Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease

The aim of the present study was to gain insight into the neuroprotection effects and mechanism of thiazolidinedione pioglitazone in both in vitro and in vivo MPP(+)/MPTP induced PD models. In vivo experimental results showed that oral treatment of pioglitazone resulted in significant improvements i...

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Detalles Bibliográficos
Autores principales: Wang, Yanqin, Zhao, Weilin, Li, Ge, Chen, Jinhu, Guan, Xin, Chen, Xi, Guan, Zhenlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357540/
https://www.ncbi.nlm.nih.gov/pubmed/28356907
http://dx.doi.org/10.1155/2017/4089214