Casein kinase 2 controls the survival of normal thymic and leukemic γδ T cells via promotion of AKT signaling

The thymus is the major site for normal and leukemic T-cell development. The dissection of the molecular determinants of T-cell survival and differentiation is paramount for the manipulation of healthy or transformed T cells in cancer (immuno)therapy. Casein kinase 2 (CK2) is a serine/threonine prot...

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Detalles Bibliográficos
Autores principales: Ribeiro, S T, Tesio, M, Ribot, J C, Macintyre, E, Barata, J T, Silva-Santos, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357576/
https://www.ncbi.nlm.nih.gov/pubmed/27899804
http://dx.doi.org/10.1038/leu.2016.363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357576/
https://www.ncbi.nlm.nih.gov/pubmed/27899804
http://dx.doi.org/10.1038/leu.2016.363

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