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Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow

Breast cancer cells frequently home to the bone marrow, where they may enter a dormant state before forming a bone metastasis. Several members of the interleukin-6 (IL-6) cytokine family are implicated in breast cancer bone colonization, but the role for the IL-6 cytokine leukemia inhibitory factor...

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Detalles Bibliográficos
Autores principales: Johnson, Rachelle W., Finger, Elizabeth C., Olcina, Monica M., Vilalta, Marta, Aguilera, Todd, Miao, Yu, Merkel, Alyssa R., Johnson, Joshua R., Sterling, Julie A., Wu, Joy Y., Giaccia, Amato J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357601/
https://www.ncbi.nlm.nih.gov/pubmed/27642788
http://dx.doi.org/10.1038/ncb3408