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In vivo Efficacy and Pharmacokinetics of Optimized Apidaecin Analogs

Proline-rich antimicrobial peptides (PrAMPs) represent promising alternative therapeutic options for the treatment of multidrug-resistant bacterial infections. PrAMPs are predominantly active against Gram-negative bacteria by inhibiting protein expression via at least two different modes of action,...

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Detalles Bibliográficos
Autores principales: Schmidt, Rico, Knappe, Daniel, Wende, Elisabeth, Ostorházi, Eszter, Hoffmann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357639/
https://www.ncbi.nlm.nih.gov/pubmed/28373972
http://dx.doi.org/10.3389/fchem.2017.00015