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In vivo Efficacy and Pharmacokinetics of Optimized Apidaecin Analogs
Proline-rich antimicrobial peptides (PrAMPs) represent promising alternative therapeutic options for the treatment of multidrug-resistant bacterial infections. PrAMPs are predominantly active against Gram-negative bacteria by inhibiting protein expression via at least two different modes of action,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357639/ https://www.ncbi.nlm.nih.gov/pubmed/28373972 http://dx.doi.org/10.3389/fchem.2017.00015 |