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In vivo Efficacy and Pharmacokinetics of Optimized Apidaecin Analogs

Proline-rich antimicrobial peptides (PrAMPs) represent promising alternative therapeutic options for the treatment of multidrug-resistant bacterial infections. PrAMPs are predominantly active against Gram-negative bacteria by inhibiting protein expression via at least two different modes of action,...

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Detalles Bibliográficos
Autores principales:	Schmidt, Rico, Knappe, Daniel, Wende, Elisabeth, Ostorházi, Eszter, Hoffmann, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357639/ https://www.ncbi.nlm.nih.gov/pubmed/28373972 http://dx.doi.org/10.3389/fchem.2017.00015

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