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Impact of high cholesterol and endoplasmic reticulum stress on metabolic diseases: An updated mini-review
Endoplasmic reticulum (ER) is the major site of protein folding and calcium storage. Beside the role of ER in protein homeostasis, it controls the cholesterol production and lipid-membrane biosynthesis as well as surviving and cell death signaling mechanisms in the cell. It is well-documented that e...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357672/ https://www.ncbi.nlm.nih.gov/pubmed/28319895 http://dx.doi.org/10.1016/j.redox.2017.02.025 |