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Resolvin D1 via prevention of ROS-mediated SHP2 inactivation protects endothelial adherens junction integrity and barrier function

Resolvins are a novel class of lipid mediators that play an important role in the resolution of inflammation, although the underlying mechanisms are not very clear. To explore the anti-inflammatory mechanisms of resolvins, we have studied the effects of resolvin D1 (RvD1) on lipopolysaccharide (LPS)...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Rima, Raghavan, Somasundaram, Rao, Gadiparthi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357675/
https://www.ncbi.nlm.nih.gov/pubmed/28319894
http://dx.doi.org/10.1016/j.redox.2017.02.023