Time- and cell-resolved dynamics of redox-sensitive Nrf2, HIF and NF-κB activities in 3D spheroids enriched for cancer stem cells

Cancer cells have an altered redox status, with changes in intracellular signaling pathways. The knowledge of how such processes are regulated in 3D spheroids, being well-established tumor models, is limited. To approach this question we stably transfected HCT116 cells with a pTRAF reporter that ena...

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Detalles Bibliográficos
Autores principales: Kipp, Anna P., Deubel, Stefanie, Arnér, Elias S.J., Johansson, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357678/
https://www.ncbi.nlm.nih.gov/pubmed/28319891
http://dx.doi.org/10.1016/j.redox.2017.03.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357678/
https://www.ncbi.nlm.nih.gov/pubmed/28319891
http://dx.doi.org/10.1016/j.redox.2017.03.013

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