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Integrin Beta 3 Regulates Cellular Senescence by Activating the TGF-β Pathway
Cellular senescence is an important in vivo mechanism that prevents the propagation of damaged cells. However, the precise mechanisms regulating senescence are not well characterized. Here, we find that ITGB3 (integrin beta 3 or β3) is regulated by the Polycomb protein CBX7. β3 expression accelerate...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357738/ https://www.ncbi.nlm.nih.gov/pubmed/28273461 http://dx.doi.org/10.1016/j.celrep.2017.02.012 |