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Lysine-specific demethylase KDM3A regulates ovarian cancer stemness and chemoresistance

Ovarian cancer is the leading cause of death among all gynecological malignancies due to the development of acquired chemoresistance and disease relapse. Although the role of cancer stem cells (CSCs), a subset of tumor cells with the self-renewal and differentiation capabilities, in therapeutic resi...

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Detalles Bibliográficos
Autores principales: Ramadoss, S, Sen, S, Ramachandran, I, Roy, S, Chaudhuri, G, Farias-Eisner, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357761/
https://www.ncbi.nlm.nih.gov/pubmed/27694900
http://dx.doi.org/10.1038/onc.2016.320