Roles and Modalities of Ectonucleotidases in Remodeling the Multiple Myeloma Niche

Ectoenzymes are cell surface molecules, which represent functional bridges between the environment and the cytoplasm. One set of ectoenzymes—CD39, CD38, CD203a, and CD73—leads to the generation of adenosine (ADO) by metabolizing ATP and NAD(+). While ADO is known to control inflammation and suppress...

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Detalles Bibliográficos
Autores principales: Chillemi, Antonella, Quarona, Valeria, Antonioli, Luca, Ferrari, Davide, Horenstein, Alberto L., Malavasi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357780/
https://www.ncbi.nlm.nih.gov/pubmed/28373875
http://dx.doi.org/10.3389/fimmu.2017.00305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357780/
https://www.ncbi.nlm.nih.gov/pubmed/28373875
http://dx.doi.org/10.3389/fimmu.2017.00305

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