DNA methylation signatures in peripheral blood strongly predict all-cause mortality

DNA methylation (DNAm) has been revealed to play a role in various diseases. Here we performed epigenome-wide screening and validation to identify mortality-related DNAm signatures in a general population-based cohort with up to 14 years follow-up. In the discovery panel in a case-cohort approach, 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yan, Wilson, Rory, Heiss, Jonathan, Breitling, Lutz P., Saum, Kai-Uwe, Schöttker, Ben, Holleczek, Bernd, Waldenberger, Melanie, Peters, Annette, Brenner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357865/
https://www.ncbi.nlm.nih.gov/pubmed/28303888
http://dx.doi.org/10.1038/ncomms14617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357865/
https://www.ncbi.nlm.nih.gov/pubmed/28303888
http://dx.doi.org/10.1038/ncomms14617

Ejemplares similares