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Deep-brain imaging via epi-fluorescence Computational Cannula Microscopy

Here we demonstrate widefield (field diameter = 200 μm) fluorescence microscopy and video imaging inside the rodent brain at a depth of 2 mm using a simple surgical glass needle (cannula) of diameter 0.22 mm as the primary optical element. The cannula guides excitation light into the brain and the f...

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Detalles Bibliográficos
Autores principales: Kim, Ganghun, Nagarajan, Naveen, Pastuzyn, Elissa, Jenks, Kyle, Capecchi, Mario, Shepherd, Jason, Menon, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357895/
https://www.ncbi.nlm.nih.gov/pubmed/28317915
http://dx.doi.org/10.1038/srep44791