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Predicting siRNA efficacy based on multiple selective siRNA representations and their combination at score level

Small interfering RNAs (siRNAs) may induce to targeted gene knockdown, and the gene silencing effectiveness relies on the efficacy of the siRNA. Therefore, the task of this paper is to construct an effective siRNA prediction method. In our work, we try to describe siRNA from both quantitative and qu...

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Detalles Bibliográficos
Autores principales: He, Fei, Han, Ye, Gong, Jianting, Song, Jiazhi, Wang, Han, Li, Yanwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357899/
https://www.ncbi.nlm.nih.gov/pubmed/28317874
http://dx.doi.org/10.1038/srep44836