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Bacterial secretion system skews the fate of Legionella-containing vacuoles towards LC3-associated phagocytosis

The evolutionarily conserved processes of endosome-lysosome maturation and macroautophagy are established mechanisms that limit survival of intracellular bacteria. Similarly, another emerging mechanism is LC3-associated phagocytosis (LAP). Here we report that an intracellular vacuolar pathogen, Legi...

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Detalles Bibliográficos
Autores principales: Hubber, Andree, Kubori, Tomoko, Coban, Cevayir, Matsuzawa, Takeshi, Ogawa, Michinaga, Kawabata, Tsuyoshi, Yoshimori, Tamotsu, Nagai, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357938/
https://www.ncbi.nlm.nih.gov/pubmed/28317932
http://dx.doi.org/10.1038/srep44795