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KUS121, a VCP modulator, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress

Ischemic neural damages cause several devastating diseases, including brain stroke and ischemic retinopathies, and endoplasmic reticulum (ER) stress has been proposed to be the underlying mechanism of the neuronal cell death of these conditions. We previously synthesized Kyoto University substances...

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Detalles Bibliográficos
Autores principales: Hata, Masayuki, Ikeda, Hanako O., Kikkawa, Chinami, Iwai, Sachiko, Muraoka, Yuki, Hasegawa, Tomoko, Kakizuka, Akira, Yoshimura, Nagahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357950/
https://www.ncbi.nlm.nih.gov/pubmed/28317920
http://dx.doi.org/10.1038/srep44873