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Kidney-specific transposon-mediated gene transfer in vivo

Methods enabling kidney-specific gene transfer in adult mice are needed to develop new therapies for kidney disease. We attempted kidney-specific gene transfer following hydrodynamic tail vein injection using the kidney-specific podocin and gamma-glutamyl transferase promoters, but found expression...

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Detalles Bibliográficos
Autores principales: Woodard, Lauren E., Cheng, Jizhong, Welch, Richard C., Williams, Felisha M., Luo, Wentian, Gewin, Leslie S., Wilson, Matthew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357952/
https://www.ncbi.nlm.nih.gov/pubmed/28317878
http://dx.doi.org/10.1038/srep44904