Double knockout of Bax and Bak from kidney proximal tubules reduces unilateral urethral obstruction associated apoptosis and renal interstitial fibrosis

Interstitial fibrosis, a common pathological feature of chronic kidney diseases, is often associated with apoptosis in renal tissues. To determine the associated apoptotic pathway and its role in renal interstitial fibrosis, we established a mouse model in which Bax and Bak, two critical genes in th...

Descripción completa

Detalles Bibliográficos
Autores principales: Mei, Shuqin, Li, Lin, Wei, Qingqing, Hao, Jielu, Su, Yunchao, Mei, Changlin, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357962/
https://www.ncbi.nlm.nih.gov/pubmed/28317867
http://dx.doi.org/10.1038/srep44892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357962/
https://www.ncbi.nlm.nih.gov/pubmed/28317867
http://dx.doi.org/10.1038/srep44892

Ejemplares similares