Altered CO (2) sensitivity of connexin26 mutant hemichannels in vitro

Connexin26 (Cx26) mutations underlie human pathologies ranging from hearing loss to keratitis ichthyosis deafness (KID) syndrome. Cx26 hemichannels are directly gated by CO (2) and contribute to the chemosensory regulation of breathing. The KID syndrome mutation A88V is insensitive to CO (2), and ha...

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Detalles Bibliográficos
Autores principales: de Wolf, Elizabeth, van de Wiel, Joseph, Cook, Jonathan, Dale, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357999/
https://www.ncbi.nlm.nih.gov/pubmed/27884957
http://dx.doi.org/10.14814/phy2.13038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357999/
https://www.ncbi.nlm.nih.gov/pubmed/27884957
http://dx.doi.org/10.14814/phy2.13038

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