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Altered CO (2) sensitivity of connexin26 mutant hemichannels in vitro
Connexin26 (Cx26) mutations underlie human pathologies ranging from hearing loss to keratitis ichthyosis deafness (KID) syndrome. Cx26 hemichannels are directly gated by CO (2) and contribute to the chemosensory regulation of breathing. The KID syndrome mutation A88V is insensitive to CO (2), and ha...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357999/ https://www.ncbi.nlm.nih.gov/pubmed/27884957 http://dx.doi.org/10.14814/phy2.13038 |