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Urinary collagen degradation products as early markers of progressive renal fibrosis

BACKGROUND: Renal fibrogenesis is associated with increased ECM remodeling and release of collagen fragments in urine in progressive renal disease. We investigated the diagnostic value of urinary collagen degradation products in a proteinuria-driven fibrosis rat model with and without anti-fibrotic...

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Detalles Bibliográficos
Autores principales: Hijmans, Ryanne S., Rasmussen, Daniel Guldager Kring, Yazdani, Saleh, Navis, Gerjan, van Goor, Harry, Karsdal, Morten Asser, Genovese, Federica, van den Born, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358042/
https://www.ncbi.nlm.nih.gov/pubmed/28320405
http://dx.doi.org/10.1186/s12967-017-1163-2