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Genome-independent hypoxic repression of estrogen receptor alpha in breast cancer cells
BACKGROUND: About 75–80% of breast tumors express the estrogen receptor alpha (ER-α) and are treated with endocrine-target therapeutics, making this the premier therapeutic modality in the breast cancer clinic. However, acquired resistance is common and about 20% of resistant tumors loose ER-α expre...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358051/ https://www.ncbi.nlm.nih.gov/pubmed/28320353 http://dx.doi.org/10.1186/s12885-017-3140-9 |