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Self-organising aggregates of zebrafish retinal cells for investigating mechanisms of neural lamination

To investigate the cell-cell interactions necessary for the formation of retinal layers, we cultured dissociated zebrafish retinal progenitors in agarose microwells. Within these wells, the cells re-aggregated within hours, forming tight retinal organoids. Using a Spectrum of Fates zebrafish line, i...

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Detalles Bibliográficos
Autores principales: Eldred, Megan K., Charlton-Perkins, Mark, Muresan, Leila, Harris, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358108/
https://www.ncbi.nlm.nih.gov/pubmed/28174240
http://dx.doi.org/10.1242/dev.142760