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Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells

Cardiomyocytes and endothelial cells in the heart are in close proximity and in constant dialogue. Endothelium regulates the size of the heart, supplies oxygen to the myocardium and secretes factors that support cardiomyocyte function. Robust and predictive cardiac disease models that faithfully rec...

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Detalles Bibliográficos
Autores principales: Giacomelli, Elisa, Bellin, Milena, Sala, Luca, van Meer, Berend J., Tertoolen, Leon G. J., Orlova, Valeria V., Mummery, Christine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358113/
https://www.ncbi.nlm.nih.gov/pubmed/28279973
http://dx.doi.org/10.1242/dev.143438