Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage

NIPBL is required to load the cohesin complex on to DNA. While the canonical role of cohesin is to couple replicated sister chromatids together until the onset of mitosis, it also promotes tolerance to DNA damage. Here, we show that NIPBL is recruited to DNA damage throughout the cell cycle via inde...

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Detalles Bibliográficos
Autores principales: Bot, Christopher, Pfeiffer, Annika, Giordano, Fosco, Manjeera, Dharani E., Dantuma, Nico P., Ström, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358341/
https://www.ncbi.nlm.nih.gov/pubmed/28167679
http://dx.doi.org/10.1242/jcs.197236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358341/
https://www.ncbi.nlm.nih.gov/pubmed/28167679
http://dx.doi.org/10.1242/jcs.197236

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