Monoubiquitylation of histone H2B contributes to the bypass of DNA damage during and after DNA replication

DNA lesion bypass is mediated by DNA damage tolerance (DDT) pathways and homologous recombination (HR). The DDT pathways, which involve translesion synthesis and template switching (TS), are activated by the ubiquitylation (ub) of PCNA through components of the RAD6-RAD18 pathway, whereas the HR pat...

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Detalles Bibliográficos
Autores principales: Hung, Shih-Hsun, Wong, Ronald P., Ulrich, Helle D., Kao, Cheng-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358361/
https://www.ncbi.nlm.nih.gov/pubmed/28246327
http://dx.doi.org/10.1073/pnas.1612633114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358361/
https://www.ncbi.nlm.nih.gov/pubmed/28246327
http://dx.doi.org/10.1073/pnas.1612633114

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